Evaluation of IL-12/23-IFN-g axis in Brazilian adult patients with recurrent mycobacteriosis
نویسنده
چکیده
Background The Mendelian Susceptibility to Mycobacterial Diseases (MSMD) is a rare congenital syndrome that confers a predisposition to recurrent infections by mycobacteria. All genetic defects that lead to MSMD produce changes at IL-12/23-IFN-g axis. We aimed to evaluate the IL-12/ 23-IFN-g axis in adult patients with recurrent mycobacterial infections in order to identify possible MSMD patients.
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